Research

Calgary Bone Health Study Bone Microarchitecture

CaBHS A population-based study investigating the variation of bone across the lifespan so that we can determine who might be at risk for a fragility fracture.

Knee ACL Injuries and OA SALTAC II

SALTAC II We know that knee injuries affect all the tissues in the joint, so this study explores the role bone plays in the potential developemnt of osteoarthritis.

Opportunistic CT Hip and Spine BMD

RETRO CT scans are done in the healthcare system for many reasons, so we do opportunistic CT to reuse them to determine their bone health.

Astronauts Bone Microarchitecture in Space

TBONE Astronauts lose bone in space due to microgravity, so we study how their microarchitecture changes in space and how it recovers when they return to Earth.

Predicting Hip Fractures Microarchitecture for Fracture Prediction

HipFX We used new morphological parameters and machine learning to predict when a person is at risk of a hip fracture based on their microarchitecture.

Calgary Vitamin D Study Effects of Vitamin D Supplementation on Bone

VITD A 3-year double-blind randomized controlled trial to study the effects of low, medium and high vitamin D supplementation on bone health using HR-pQCT.

Finite Elements Image-Based Bone Strength Analysis

FAIM We combine medical imaging with finite element analysis to non-invasively determine bone strength of people for the prediction of fracture.

Quantitative CT Establishing BMD from clinical CT

ARTININ We use clinical CT scans for developing asynchronous and phantom-based approaches to measure volumetric bone mineral density.

Finite Element Analysis Numerics88 FAIM

This free package can be installed on MacOS, Linux or Windows for solving image-based FE models. It includes n88tools/vtkbone that reads AIM files.

Opportunistic CT Ogo Repo

An open-source repository for working with computed tomography data designed to support opportunistic screening. Includes various calibration methods.

HR-pQCT Knee Segmentation Knee Seg Repo

A repository using machine learning to segment the knee and identify regions of interest in each of the four compartments for morphological analysis.

HR-pQCT Radius & Tibia Seg Radius/Tibia Seg Repo

Machine learning for segmenting the distal radius and distal tibia from HR-pQCT scans as an alternative to the morphological processing approach.

Bonelab Toolbox Bonelab Repo

Open-source repository of tools for image processing for microCT, HR-pQCT, or similar data. It has tools for 3D registration and other useful applications.

Tomographic Reconstruction Athabasca Recon Repo

An open-source package for computed tomography reconstruction using filtered back-projection. It is designed for parallel X-rays from synchrotron acquisition.

Normative Reference Data Normative Repo

A comprehensive online tool that generates reference plots for HR-pQCT data and DXA data, and reports for bone phenotyping and µFRAC fracture estimation.

Cortical Bone Mapping See Bonelab Repo

Building on the method devised by Graham Treece, it a model-based approach to extracting cortical thickness and the periosteal surface for HR-pQCT and CT.